26 April 2025 The Future is the Product of the Past

World’s Oldest Arrow Poison Discovered in South Africa, Dating Back 7,000 Years

In a groundbreaking discovery, archaeologists excavating Kruger Cave in South Africa have identified what may be the oldest confirmed multi-component arrow poison in the world, dating back 7,000 years. The femur bone of an unspecified antelope, found during a 1983 excavation, contained three modified bone arrowheads embedded in its marrow cavity.

After lying in storage at the University of the Witwatersrand for nearly four decades, renewed archaeological investigations in 2022 prompted scientists to re-examine the femur and its contents. A team from the University of Johannesburg, led by Associate professor Justin Bradfield focused on organic materials, conducted a detailed analysis of the chemical matrix surrounding the arrowheads.

The research revealed a complex recipe combining at least two toxic plant ingredients, including cardiac glycosides known to disrupt heart function. Notably, digitoxin and strophanthidin were identified, alongside ricinoleic acid, a by-product of the toxic lectin ricin. The presence of these compounds suggests that ancient peoples were adept at mixing various plant toxins to create effective hunting poisons.

Interestingly, none of the plant species containing these toxins are native to the Kruger Cave area, indicating that the ingredients may have been sourced from distant locations or through established trade networks. This finding challenges previous assumptions about the movement of non-domestic plants in southern Africa during this period.

Recent findings have revealed that the long-distance transport of non-domestic plants in Africa may have occurred much earlier than previously thought. While researchers have long known that the transport of seashells as ornaments and currency was common throughout the continent well before 7,000 years ago, the movement of non-native plants at such an early date was unexpected.

There is faded rock art at the site (one of only seven rock art sites in the Magaliesberg), some of which was recorded by Harold Pager who worked at the site in the 1970s. He recorded 57 images painted on the walls, mostly human figures but also some animals and birds. Very few painted images are visible now. Photo Credit: The South African Archaeological Society
There is faded rock art at the site (one of only seven rock art sites in the Magaliesberg), some of which was recorded by Harold Pager who worked at the site in the 1970s. He recorded 57 images painted on the walls, mostly human figures but also some animals and birds. Very few painted images are visible now. Photo Credit: The South African Archaeological Society

This discovery highlights the advanced knowledge of ancient peoples regarding plant acquisition and usage. The ability to identify which plants to gather, where to locate them, and how to utilize them effectively underscores the depth of traditional pharmacological knowledge systems that have existed for millennia. This insight not only reshapes our understanding of ancient trade practices but also emphasizes the sophistication of early human societies in their interactions with the natural world.

The study also highlights the significance of traditional pharmacological knowledge among ancient populations, as well as the potential of archaeobotany and organic chemistry to enhance our understanding of historical practices. The ability to create complex recipes for poisons, adhesives, and medicines reflects advanced cognitive capacities of the makers.

This discovery adds to the growing body of evidence regarding the use of poisons in hunting technology, which has been documented across various cultures worldwide. The findings at Kruger Cave illuminate ancient hunting practices while also demonstrating the advanced understanding of natural resource utilization by early human societies.

Bradfield, J., Dubery, I. A., & Steenkamp, P. A. (2024). A 7,000-year-old multi-component arrow poison from Kruger Cave, South Africa. iScience, 27(12), 111438. doi:10.1016/j.isci.2024.111438

Related Articles

Two mysterious stone balls were found buried in a tomb dating to 3500 BC in Orkney

2 September 2021

2 September 2021

In Orkney, archaeologists discovered two carved stone balls in a tomb dating from 3500 BC. Archaeologists are on-site at Tresness,...

“Land of the Thousand Temples” Kancheepuram in India

20 May 2021

20 May 2021

Kancheepuram, one of the most sacred and religious Hindu pilgrim centers in India is also called the ‘Land of the...

Israeli researchers create AI to translate ancient cuneiform Akkadian texts

4 May 2023

4 May 2023

Israeli experts have created a program to translate an ancient language that is difficult to decipher, allowing automatic and accurate...

Lead Glass Jewelry was Mass-Produced in Medieval Poland from Local Raw Material

7 April 2025

7 April 2025

Recent archaeological research has unveiled significant insights into the mass production of lead glass jewelry in medieval Poland, confirming that...

Roman Bath and Magnificent Mosaics Used as Stables by the Villagers For Many Years

3 January 2025

3 January 2025

Archaeological excavations in the ancient city of Herakleia in Muğla’s Milas district in western Türkiye unearthed a striking discovery from...

Evil-Wisher Well: Ancient curse tablets 2,500-year-old found in a well in Athens

14 July 2022

14 July 2022

30 ancient curse tablets were found at the bottom of a 2500-year-old well in ancient Athens. In 2020, Archaeologists from...

New AI Tool ‘Fragmentarium’ Brings Ancient Babylonian Texts Together

6 February 2023

6 February 2023

An artificial intelligence (AI) bot was developed by linguists at the Institute for Assyriology at Ludwig Maximilian University in Germany...

Rare African Script Offers Clues to the Evolution of Writing Systems

4 February 2022

4 February 2022

The world’s very first invention of writing took place over 5000 years ago in the Middle East, before it was...

The Secret of the Shipwrecks at Theodosius Harbor: 1,600 Years Old Women’s Sandals and Comb

11 April 2023

11 April 2023

The 1,600-year-old sandals and comb unearthed during the excavations of Theodosius Harbor (Portus Theodosiacus), the second-biggest harbor built on the...

Neolithic village discovered in northeastern France after 150 years of research

29 August 2023

29 August 2023

Archaeologists have uncovered traces of a permanent settlement in the vast Neolithic site of the Marais de Saint-Gond in northeastern...

Lost 4,000-Year-Old Bronze Age Settlement Uncovered at Khaybar Oasis in Northern Saudi Arabia

31 October 2024

31 October 2024

A team of archaeologists led by Guillaume Charloux of France’s National Center for Scientific Research (CNRS) announced Wednesday the discovery...

The Only Known Roman Brewery, Discovered in Central Italy

6 July 2024

6 July 2024

Archaeologists from the University of Macerata have discovered the only brewery from the Roman era found to date on the...

Outstanding Bronze Age artifacts discovered in the Auvergne-Rhône-Alpes region of France

23 August 2021

23 August 2021

Hundreds of bronze objects have been discovered buried in pottery in the Auvergne-Rhône-Alpes region of France. The research team, led...

From ‘Empty Lands’ to Rich History: Discovery of the First Bronze Age Settlement in Maghreb, Dating to 2,000 BC

15 March 2025

15 March 2025

Researchers at the University of Barcelona have made a remarkable discovery: the first Bronze Age settlement in the Maghreb region...

A Remarkable Discovery from a Gaza Shipwreck: Olive Pits from 1100 Years Ago

10 March 2025

10 March 2025

The recent underwater excavations off the coast of Türkiye have unveiled an extraordinary find that has captivated scientists: olive pits...

  • These three toxins from native African plants being in use as a poison isn’t shocking in the least. Africa’s climate has changed over time, as have the civilizations that developed there. One thing that hasn’t changed? Our ability to underestimate our ancestors knowledge, ingenuity, culture and wide ranging travels.
    All three of these plants are easily grown from seed, widely adapted to a variety of climate variation. Castor and Foxglove are seen in gardens all over the world. Strophanthus is a bit finicky to grow, needing humidity and warm conditions, but they grow from Equatorial Africa and as far South as South Africa.
    South Africa is the perfect place to grow these three native African plants.
    If you want an example of how fast plant seeds of high value can travel. The hot peppers of the America’s have been an integral part of Chinese cuisine for at least 400 years. But it is entirely possible that Chinese ships were trading in the America’s far earlier than Columbus It is a form of conceit that we assume we are the only humans with intellectual curiosity. and the desire to act that curiosity. It is evident to me that intellectual curiosity is fading in the modern world, we are no longer who humans have always been; the most curious and innovative of all animals.